Manufacturing skin whitening sunscreen from kojic acid extracted from a local isolate of fungus Morchella importuna for combination skin type

Section: Article
Issue
Vol. 21 No. 3 (2025): Volume 21 Issue 3
Published
Sep 1, 2025
Pages
619-631

Abstract

Continuous exposure to sunlight will expose  skin to various problems, including hyperpigmentation, premature winkles, sunburns, and skin cancer. Thus, in order to protect  skin from these risks, sunscreen should be used to have a healthy and bright skin. Therefore,  a skin whitening sunscreen was manufactured from kojic acid extract of a local isolate for  Morchella Importuna fungus, in addition to Vitamin E. Sensory and biochemical tests  revealed that this sunscreen has a white colour, a smooth homogeneous texture, a pH of 6.2, and a diffusion time of 12 seconds.  In addition, safety tests on rats  showed no signs of irritation, redness, or skin sensitivity during the 48- hour test duration. It was shown that  manufactured cream has a protection factor of a value of 50, which provides a 98% protection from  ultraviolet rays, while that of La Roche sunscreen was 33, which provides 97% protection. Therefore, it is advised to use this manufactured skin whitening sunscreen regularly to maintain  skin's health, improve its appearance, and lighten  skin via kojic acid use, and protecting it at the same time from  harmful ultraviolet rays, including people with combination skin types, and people who care about natural and sustainable products.

References

  1. Wacker M, Holick MF. Sunlight and Vitamin D: A global perspective for health. Dermatoendocrinol. 2013; 5(1): 51-108. Doi.10.4161/derm.24494
  2. Joshi S, Vghela K, Patel D., Mishra A, Patel, P.2024. Formulation and evaluation of poly-herbal UV protecting cream. Int. J. Pharmacognsy Pharm. Res..2024; 6(1): 26-31. Doi.10.33545/26647168.2024.v6.i1a.65
  3. Nitha B, De S, Devasagayam TPA, Janardhanan KK. Edible mushroom Morchella esculenta (L.) Pers. mycelium protects DNA and mitochondria from radiation induced damages. Indian J. Exp. Biol.2020; 58 (12): 842-847. Doi.10.56042/ijeb.v58i12.44571
  4. Sujarit K, Suwannarach N, Kumla J, Lomthong T. Mushrooms: Splendid gifts for cosmetic industry. Chiang. Mai. J. Sci.2021;48(3):699-725.
  5. Shanbhag S, Nayak A., Narayan R, Nayak UY. Anti-aging and Sunscreens: Paradigm Shift in Cosmetics. Adv. Pharm. Bull.2019; 9(3):59-348.Doi. 10.15171/apb.2019.042
  6. Ueitele ISE, Chimwamurombe PM, Kadhila-Muandingi N P. Optimization of indigenous Ganoderma lucidum productivity under cultivation in Namibia. Int. Sci. Technol. J. Namibia. 2014; 3(1): 35–41.
  7. Hasyan WJ, Abdul-Hadi SY. Evaluation the effectiveness of kojic acid which is purified from a new local fungal isolate of Morchella importuna in improving wounds healing. J. Microbiol. Biotechnol. and Food. Sci.2024 (under publication).
  8. Patel RI, Patel AM Modi BD. Formulation and evaluation of herbal sunscreen. World J. Bio. Pharm. Health Sci. 2023; 13(02):029-040. Doi.10.30574/wjbphs.2023.13.2.0061
  9. Amnuaikit T, Boonme P. Formulation and characterization of sunscreen creams with synergistic efficacy on SPF by combination of UV filters. J. Appl. Pharmaceut. Sci. 2013; 3(8):1-5. Doi.10.7324/JAPS.2013.3801
  10. Rohmani S, Kuncoro MAA. Stability and activity test of basil leaf extract handsanitizer gel. J. Pharm. Sci. Clin. Res.2019; 4(1):16-28. https://doi.org/10.20961/jpscr.v4i1.27212.
  11. El-Hag MG. Laboratory –Manual for Animal Feedstuffs Analysis and Nutritional Evaluation Techniques. Al Zaeim Al Azhari University. Depart. Animal. Prod. Khartom, North Sudan; 2022. 1-60 p.
  12. Khan Y, Imam S, Tasleem F, Abbas T, Perveen R, Siddiqui N, Abidi S, Azhar, I., (2023). Sustainable use of traditional plant extracts for the formulation of herbal shampoos. J. Hunan Univ. Nat. Sci. 2023; 50(4):1674-2974. Doi.10.55463/issn.1674-2974.50.4.14
  13. Andrea K, Katalin BB, Erzsѐbet F, Emese S, Ibolya F. Determination of the sun protection factor of sunscreens. J. Bull. Med. Sci.2022; 95(1):64-77. Doi.10.2478/orvtudert-2022-0004
  14. Sayre RM, Agin, PP, Levee GJ, Marlowe EA. Comparison of in vivo and in vitro testing of sun screening formulas. Photochem. Photobiol.1979; 29(3): 559-566. Doi.10.1111/j.1751-1097.1979.tb07090.x
  15. Ghorpade MN, Vyawhare PV, Chaudhary AB. Formulation and evaluation of herbal sunscreen cream by using Moringa Oleifera and Curcuma Longa. Int. J. Pharmaceut. Res.2024; 9(3):1783-1787.Doi. 10.35629/4494-090317831787
  16. Verda V, Leonardo W, Prismawan D, Notario D. Optimization of sunscreen cream formulation containing ethanolic extract of Avocado Leaves (Persea americana Mill.) or Mangosteen Rind (Garcinia mangostana L.) Combined with Octyl Methoxycinnamate. Galenica. J. Pharmacy.2023; 9(2):165-179. Doi.10.22487/j24428744.2023.v9.i2.16083
  17. Shah Y, Mewada R. Preparation and evaluation of herbal sunscreen creams. Int. J. Pharmaceut. Chem. Anal. 2023; 10(2):116–124. Doi.10.18231/j.ijpca.2023.021
  18. Rohmani S, Desi BA, Wardhani WD. Potassium-Azeloyl-Diglycinate BB-Cream formulation with Triethanolamine variation, and its effects on In-Vitro SPF stability and values. J. Adv. Pharm. Educ. Res.2022; 12(1):1-8. Doi.10.51847/muhp4ptold
  19. Sapiun Z, Achmadi N, Imran AK, Muindar M, Buana WAA, Nur MU, Hartati H, Kamba V, Slamet NS, Ysrafil Y, Rifai, Y. Determination of sun protection factor lotion of Pulai stem extract (Alstonia scholaris (L.) R.Br. Maced. J. Med. Sci.2022; 10(A):833-840. Doi.10.3889/oamjms.2022.9131
  20. Tiwari R, Singh I, Gupta M, Singh LP, Tiwari G. Rmulation and evaluation of herbal sunscreens: an assessment towards skin protection from ultraviolet radiation. J. Pharmacophore. 2022; 13(3): 41-49. Doi.10.51847/svzlrfmp5f
  21. Mbanga L, Mpiana PT, Mumbwa AM, Bokolo K., Mvingu K, Ngoy B, Muwawa K., Mulenga M. Sun Protection Factor (SPF) Determination of Cosmetic Formulations Made in Kinshasa (DR Congo) by In-Vitro Method using UV-VIS Spectrophotometer. J. Phys. Chem. Sci.2(1):1-5.
  22. Khairi N., as’ad,S., Djawad K, Alam, G. The determination of antioxidants activity and sunblock Sterculia populifolia extract- based cream. J. Pharm. Biomed. Res.2018; 4(1):20-26. Doi.10.18502/pbr.v4i1.142

Authors

Wisam J. Hasyan

Department of Biology, College of Education for Pure Sciences, University of Mosul, Mosul city, Iraq

Shimal Y. Abdul-Hadi

Department of Biology, College of Education for Pure Sciences, University of Mosul, Mosul city, Iraq

Identifiers

https://doi.org/10.33899/berj.2025.Vol21.Iss3.53551
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How to Cite

وسام جهاد حسيان, & شمال يونس عبد الهادي. (2025). Manufacturing skin whitening sunscreen from kojic acid extracted from a local isolate of fungus Morchella importuna for combination skin type. College of Basic Education Research Journal, 21(3), 619–631. https://doi.org/10.33899/berj.2025.Vol21.Iss3.53551